Dirico, Kenneth J. : rechercher sur Z-Library

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1

The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor

Michael P. DeNinno, Hiroko Masamune, Lois K. Chenard, Kenneth J. DiRico, Cynthia Eller, John B. Etienne, Jeanene E. Tickner, Scott P. Kennedy, Delvin R. Knight, Jimmy Kong, Joseph J. Oleynek, W. Ross

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 108 KB

english, 2006

2

Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists

Paul S. Humphries, John W. Benbow, Paul D. Bonin, David Boyer, Shawn D. Doran, Richard K. Frisbie, David W. Piotrowski, Gayatri Balan, Bruce M. Bechle, Edward L. Conn, Kenneth J. Dirico, Robert M. Oli

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 267 KB

english, 2009

3

Chemically-enabled synthesis of 1,2,3,4-tetrahydroisoquinolin-1-ones

Paul S. Humphries, Gayatri Balan, Bruce M. Bechle, Edward L. Conn, Kenneth J. Dirico, Yu Hui, Robert M. Oliver, James A. Southers, Xiaojing Yang

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 412 KB

english, 2009

4

Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor

Stepan, Antonia F., Subramanyam, Chakrapani, Efremov, Ivan V., Dutra, Jason K., O’Sullivan, Theresa J., DiRico, Kenneth J., McDonald, W. Scott, Won, Annie, Dorff, Peter H., Nolan, Charles E.

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2012

5

Metabolism-Directed Design of Oxetane-Containing Arylsulfonamide Derivatives as γ-Secretase Inhibitors

Stepan, Antonia F., Karki, Kapil, McDonald, W. Scott, Dorff, Peter H., Dutra, Jason K., DiRico, Kenneth J., Won, Annie, Subramanyam, Chakrapani, Efremov, Ivan V., O’Donnell, Christopher J.

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2011

6

Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase

Freeman-Cook, Kevin D., Amor, Paul, Bader, Scott, Buzon, Leanne M., Coffey, Steven B., Corbett, Jeffrey W., Dirico, Kenneth J., Doran, Shawn D., Elliott, Richard L., Esler, William

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 380 KB

english, 2012

7

Discovery of triazolopyrimidine-based PDE8B inhibitors: Exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes

Michael P. DeNinno, Stephen W. Wright, John B. Etienne, Thanh V. Olson, Benjamin N. Rocke, Jeffrey W. Corbett, Daniel W. Kung, Kenneth J. DiRico, Kim M. Andrews, Michele L. Millham, Janice C. Parker,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 2.00 MB

english, 2012

8

Concerted vs Stepwise Mechanisms in Dehydro-Diels–Alder Reactions

Ajaz, Aida, Bradley, Alexander Z., Burrell, Richard C., Li, William Hoi Hong, Daoust, Kimberly J., Bovee, Laura Boddington, DiRico, Kenneth J., Johnson, Richard P.

Journal:

Journal of Organic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 873 KB

english, 2011

9

Strained Cyclic Cumulene Intermediates in Diels−Alder Cycloadditions of Enynes and Diynes

Burrell, Richard C., Daoust, Kimberly J., Bradley, Alexander Z., DiRico, Kenneth J., Johnson, Richard P.

Journal:

Journal of the American Chemical Society

Année:

1996

Langue:

english

Fichier:

PDF, 76 KB

english, 1996

10

Photorearrangements of acyclic conjugated enynes: a photochemical analog of the Bergman rearrangement

Zheng, Manli, DiRico, Kenneth J., Kirchhoff, Mary M., Phillips, Kristine M., Cuff, Lisa M., Johnson, Richard P.

Journal:

Journal of the American Chemical Society

Année:

1993

Langue:

english

Fichier:

PDF, 643 KB

english, 1993

11

Synthesis of Unprotected Carboxy Indazoles via Pd-Catalyzed Carbonylation

Wainwright, Philip, Perni, Remedios, Vickers, Clare, Coffey, Steven B., Buzon, Leanne, DiRico, Kenneth, Nelson, Kendra L., Zhao, Zhengrong, Limberakis, Chris, Freeman-Cook, Kevin D., Corbett, Jeffrey

Journal:

Synthetic Communications

Année:

2012

Langue:

english

Fichier:

PDF, 273 KB

english, 2012

12

Ab Initio Conformational Analysis of trans-Cyclohexene

Johnson, Richard P., DiRico, Kenneth J.

Journal:

Journal of Organic Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 827 KB

english, 1995

13

3‘-Aminoadenosine-5‘-uronamides: Discovery of the First Highly Selective Agonist at the Human Adenosine A 3 Receptor

DeNinno, Michael P., Masamune, Hiroko, Chenard, Lois K., DiRico, Kenneth J., Eller, Cynthia, Etienne, John B., Tickner, Jeanene E., Kennedy, Scott P., Knight, Delvin R., Kong, Jimmy, Oleynek, Joseph J

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 51 KB

english, 2003

14

Human-in-the-Loop Simulation Experiment of Integrated Arrival/Departure Control Services For NextGen Operational Improvement

Hah, Sehchang, Willems, Ben, Mueller, Gary, Johnson, Daniel R., Schulz, Kenneth, DiRico, John, Hallman, Kevin, Maliko-Abraham, Helene, O’Brien, T. G., Alvidrez, Sonia, Bastholm, Robert, Dworsky, Matth

Journal:

Proceedings of the Human Factors and Ergonomics Society Annual Meeting

Année:

2017

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2017

15

Ultra-High-Throughput Acoustic Droplet Ejection-Open Port Interface-Mass Spectrometry for Parallel Medicinal Chemistry

DiRico, Kenneth J., Hua, Wenyi, Liu, Chang, Tucker, Joseph W., Ratnayake, Anokha S., Flanagan, Mark E., Troutman, Matthew D., Noe, Mark C., Zhang, Hui

Journal:

ACS Medicinal Chemistry Letters

Année:

2020

Fichier:

PDF, 3.06 MB

2020